The Northern Irishman confirmed he re-fractured the hand in training for his bout with McCreary, and believed he did so again during a fight in which he dropped the American twice with powerful body shots.
Frampton added that he would be equally happy to challenge in Belfast or NY against Herring, who has won 21 of his 23 fights.
It was a solid performance and marked a winning return for the former two-weight world champion, who hadn't fought in nearly a year.
If the 32-year-old was to win the super featherweight belt he would become Ireland's first-ever three-weight world champion as he has previously held world titles at super-bantamweight and featherweight.More news: Detroit faces Philadelphia, seeks to break 7-game skid
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"McCreary seems to be getting comfort out of me looking to that fight and he thinks I'm looking past him, but I'm definitely not, I'm 100% focused on Tyler McCreary". "The pressure is on as I know I have to beat him, and I'll perform well under pressure". I'm not the champion.
"I want to get that fight".
"My hand wasn't great coming into the camp so it's always a bit softer hitting a body than a head. I just wanted to be safe with my hands".
'I feel like I hurt it again in the second round so that's why it wasn't the most exciting fight. I'm preparing for a tough fight, and like I said I'm not taking my eye off the ball.