Goals from Mason Greenwood, Anthony Martial and Marcus Rashford - starting together for the first time - paved the way for a routine win on Thursday, as United ensured their progression from Group L with two games to spare.
Lindelof is the latest on United's injury list after suffering a re-occurrence of a back injury that he had first sustained against AZ Alkmaar in October in their recent 1-0 league defeat against Bournemouth in the Premier League.
Ole Gunnar Solskjaer named a strong side that included Anthony Martial and Marcus Rashford up top, while Juan Mata and Marcos Rojo were also recalled to the United line-up. "You can't just turn that switch off and on, you've got to perform every day if you're going to be accepted in a place like this".
"Mason is going to have a very big career but sometimes it is not the right time to play him", said Solskjaer.
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'I think he lacks that little bit of composure.
If Solskjaer wants to make changes he can look to his bench, where options available include Daniel James and Jesse Lingard.
"He is very composed with his finishing".
"It is the club's philosophy - and mine - to give young players with the right attitude a chance", said Solskjaer. Hopefully today was just the start of it and we can keep improving and be more natural.
"We wanted to get through as quickly as we could and that long trip is not one you want to travel to and have to win", said Solskjaer. "I don't think he knows whether his right or left foot is the best". The good thing is he can do it at Old Trafford in front of a full crowd or 62,000, he doesn't get fazed by the occasion. He finished the game anyway. I'm managing for Man United, I'm not managing for me.
If Manchester United are to grace the Champions League in 2020-21 then they will need to sneak in "via the back door", says Paul Parker, with the Europa League presenting their only path to a standing among the continental elite.