Alexander was pronounced dead upon arrival at the hospital.
The 66-year-old experienced and licensed hunter from Yellville had embarked on a hunting expedition near the Ozark mountains in Arkansas where he shot a buck, watched as it went down, and assumed it had died.
The deer, which was not fatally injured, got back up and attacked Anderson, who suffered several puncture wounds on his body.
Alexander managed to call his wife after the attack, and first responders arrived to take him to the hospital.
He had sent a text message to his nephew to tell him he shot the deer at roughly 6:45 p.m., Keith Stephens, a spokesman for the commission, told Anadolu Agency.
Stephens also added that hunters should ensure their safety by making sure the deer is dead after being shot.More news: Prescription drug ‘Take Back Day’ lasts until 2 p.m.
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According to him, a similar incident had happened four years ago, when a person was struck by buck antlers.
The Arkansas Game and Fish Commission termed it as an odd hunting-related death that they investigated.
The buck that was shot by Alexander is still missing.
Though it's not uncommon for hunters to mistake a fallen deer as dead - experts suggest waiting a half-hour, observing the animal to confirm the kill - it is unusual for the encounter to be fatal.
The Arkansas Game and Fish Commission said it's important for hunters to make sure the deer is not moving for about 30 minutes before approaching it.
"During our hunter education classes we explain the best thing to do is approach it from behind", he said.