The U.S. Centers for Disease Control Prevention urges people in NY state and five other states not to serve or sell whole, fresh papayas imported from Mexico or food that contains papaya from Mexico.
The FDA is increasing import screening for whole, fresh papayas and will continue to investigate the cause and source of the outbreak as well as the distribution of products.
So far, no deaths are reported.
Consumers should throw the papayas away, even if some of them were eaten and no one has gotten sick, the CDC added.
Consumers should not eat papayas or fruit salads containing papayas from Mexico, the agency advised.
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These illnesses have been reported in eight states: Connecticut, Massachusetts, New York, New Jersey, Pennsylvania, Rhode Island, Florida, and Texas. When in doubt, don't eat the papaya officials said. Most illnesses have occurred since April, they said.
It also said places where papayas are stored - including countertops and refrigerator shelves - should be sanitized.
Salmonella can last four to seven days, and most recover without treatment, the agency reported.
About 450 people in the United States die from salmonella every year, FDA officials said, noting that children younger than 5, the elderly and people with weakened immune systems are most susceptible to severe illness.
"Most people with salmonellosis develop diarrhea, fever and abdominal cramps", officials said.
This investigation is ongoing and the advice will be updated when more information is available.