"I would avoid City", the former Red said on Italian broadcaster Rai Sport when asked which teams Juventus would not like to face in the quarter-finals.
This is the first time England has had four teams in the quarter-finals since Liverpool and United were joined by Arsenal and Chelsea in the 2008-09 campaign.
In 2006/07 Liverpool oversaw a convincing 4-0 aggregate triumph over PSV, then beat rivals Chelsea on penalties, but AC Milan got revenge in the final.
Elsewhere, he said a meeting between the unfancied pair of Porto and Ajax would be a welcome story for the clubs and their respective countries as one of them would at least be guaranteed a semi-final spot.
"And with the emotion of that game, the Champions League final, can those players even realistically play on the Thursday night for us?"
GETTY IMAGESLiverpool defender Virgil van Dijk heads home during their win over Bayern Munich
In particular, Mohamed Salah has struggled to find his goalscoring boots in recent weeks, with just one goal in his last seven league matches. Messi was instrumental during Barca's 5-1 Nou Camp win against Lyon on Wednesday, scoring twice and creating the others for the Spanish champions, while Ronaldo's hat-trick against Atletico Madrid in Turin 24 hours earlier was just the latest chapter in the Juventus forward's incredible Champions League story.
Man Utd are amongst Europe's elite in the quarter-finals for the first time since 2013/14, when they lost out to Bayern Munich under former manager David Moyes. It's definitely up there with United's most dazzling nights under the lights.
England beat Croatia and Spain en route to the Nations League last four, that will also see hosts Portugal play Switzerland on the other side of the bracket. Barcelona against Juventus in a possible final or semi-final.
Jose Mourinho says he would relish the prospect of two all-English Champions League quarterfinals, ahead of the draw for the competition at UEFA headquarters in Nyon, Switzerland, on Friday.More news: Connecticut Supreme Court: Suit Against AR-15 Manufacturer Can Proceed
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