Lower Risk For Parkinson's Of Over 20%?


Scientists from the Van Andel Research Institute in MI examined data on 1.7 million people in Sweden and found that having an appendectomy is linked to a 19.3 percent reduced risk of developing Parkinson's in a general population.

Parkinson's disease is an incurable brain disease that affects the senses, memory and mood.

The analysis of health records of more than 1 million individuals in Sweden found that having the appendix removed early in life is linked to a 19% reduced risk of developing Parkinson's disease. However, Labrie warned that appendectomy does not guarantee that a person will not be diagnosed with Parkinson's.

"Our findings show the appendicular appendix as the region of origin of Parkinson's and open a new path for alternative therapeutic strategies that will harness the role of the gastrointestinal system in the development of the disease".

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Could the appendix be the cause of Parkinson's? "That's what we plan to look at next - which factor or factors tip the scale in favor of Parkinson's". Also, the scientists found some differences in protein structure between healthy people and people with Parkinson's disease.

These proteins are found in the appendix. The researchers believe that Parkinson's might be triggered during the rare occurrence that the protein escapes the appendix. Additionally, he would have liked to see more information on how the age when the appendectomy was performed changed the risk of developing Parkinson's disease, as well as potential reasons for the differing effect in rural areas. Removing the appendix doesn't completely eliminate the risk, and it's normal for the clumped proteins to appear in the appendix.

Viviane Labrie, an assistant professor at Van Andel Research Institute in MI and senior author of the study, said: "Despite having a reputation as largely unnecessary, the appendix actually plays a major part in our immune systems, in regulating the makeup of our gut bacteria and now, as shown by our work, in Parkinson's disease".

"We're not saying to go out and get an appendectomy", said Viviane Labrie of Michigan's Van Andel Research Institute.

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