The centre-back played in the Netherlands' 3-0 UEFA Nations League victory over Germany on Saturday.
And though the withdrawals of both Van Dijk and Salah should not be considered positive as they are due to injuries, that they are seen as precautionary is a boost.
Since its origin, the rivalry has had many standout moments, that 1974 final, the Dutch win in Germany during Euro 1988 or that quarterfinal during Italia '90 where physicality beat football.
These are dark days for the Germans, still reeling from their woeful World Cup display when they crashed out early after finishing bottom of their group.
They suffered a shock exit in the group phase of the 2018 tournament in Russian Federation and this loss leaves them with only one point from their opening two Nations League matches.
Depay added a second late on from a quick counter-attack after being set up by Quincy Promes.More news: Trump says 'rogue killers' may be behind Khashoggi disappearance
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They face world champions and group leaders France in the competition in Paris on Tuesday.
Loews contract runs until 2022, having been extended for two years in May.
Yet again, his senior players let him down as the Bayern Munich axis of Manuel Neuer, Jerome Boateng, Mats Hummels and Thomas Mueller struggled.
Striker Timo Werner said: "We missed out on scoring when we had the chances to do so".
The Dutch went ahead after 30 minutes when Babel out-jumped Germany midfielder Joshua Kimmich to the ball, headed onto the post and Van Dijk pounced on the rebound.
Depay then hit the crossbar, before Wijnaldum added another in the third minute of stoppage time.