Among them is 2015 FedEx champion Jordan Spieth, who would end up 31st in the standings and miss the Tour Championship for the first time since turning pro and playing a full season in 2013.
Bradley, who shot a final round 6-under 64 to finish at 20-under par, thrust his arms toward the gray sky and drizzle in celebration and waved his family onto the 18th hole.
Rose was at 17-under 193.
However, Rose's approach stalled in the wind and landed short of the green, and his mis-judged pitch stopped 15 feet from the hole before his par-putt caught a big piece of the hole but stayed out.
Bradley, 32, burst onto the scene with a major victory at the 2011 PGA Championship, but until Monday had not won since 2012. And that's so huge for a player where I am at this point because then I can play my way back into the top 50.
"I just wish I could have enjoyed the moment maybe, and this just slightly dampens it. Because for a little while, I didn't know if I was going to be able to get back to this spot, and today I did it".More news: Hurricane Florence: Headed To North Carolina As Category 4 Storm
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"I'm disappointed right now".
Keegan Bradley had bottomed out, crashing from the high of winning the PGA Championship to tumbling out of the 100 in the world.
"But obviously it's a big consolation being world No 1". "And I don't think that would have been good enough".
He is now projected to finish 31st in the FedExCup standings and miss out on the Tour Championship as only the Top 30 players advance to the season finale at Atlanta's East Lake.
"I was in control of my own destiny and didn't have it this week, " said Spieth, who shot 73 on Monday at Aronimink Golf Club to tie for 54th. "This dream that we've all thought about at some point in our lives. That's what excites me, but the quest to get better is why I wake up in the morning".
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