Adding to that were fresh concerns over the condition of his knees.
Light rain began to fall just as the Bangladesh innings ended, keeping the players from the field for some time and causing the West Indies' target to be revised to 91 from 11 overs. After the match, a "bit worried" Russell, who was promoted to No. 3, said that while he wasn't yet 100% fit, he was "happy enough to be playing at probably 95%".
However, they will be favourites to get the better of Bangladesh, with the likes of AndrÈ Russell and Marlon Samuels available following injury, and white-ball specialists Rovman Powell and Kesrick Williams also in the line-up.
The incident could be recorded as one of the worst deliveries in worldwide cricket. Thereafter, Bangladesh were reliant entirely on Mahmudullah to bail them out, and while he made a sprightly 27-ball 35, lack of support from the others did Bangladesh in.
Though not in the squad, ODI captain Mashrafe Mortaza wasn't particularly confident when speaking ahead of the three-game series, saying: "With the T20I series coming up, it won't be easy to play against a side like West Indies". This would be Nurse's only over, which Brathwaite later put down to "tactics".More news: New York Yankees acquire Lance Lynn from Minnesota Twins for 2 prospects
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From there, Andre Russell steadied the ship with some powerful hitting and forged a partnership with the experienced Marlon Samuels. Liton Das and Shakib played a bit where both of them added nearly 40 runs. This spell brought Bangladesh 38 runs off 28 balls, before Keemo Paul's raw pace accounted for the pair off successive deliveries in the sixth over.
The right-handed Das had struck three fours in a 21-ball knock when he tried to pull a quick one from Paul and miscued to Andre Fletcher at square leg.
Iqbal has always been the crown jewel of Bangladesh's batting. But wicketkeeper Chadwick Walton will make his return as West Indies hopes to gain an advantage before the T20 series shifts to the United States.
Needing to score at just over eight runs an over, the Windies got 10 runs from the first over but then lost two wickets in the second when Evin Lewis (2) top-edged left-arm seamer Mustafizur Rahman to third man and Fletcher (7) edged a cut behind. Russell and Samuels played long where Samuels scored 26 runs but Russell remained not out with 35 runs so far.