"Maintaining his vital organ functions continues to remain a challenge considering his age related ailments", it said.
#03:50 PM: Stalin requests CM Palaniswami for a place along Marina beach: DMK working president MK Stalin has reportedly requested Tamil Nadu Chief Minister Edappadi K Palaniswami for a place along the Marina beach in Chennai, where they can build a memorial for the ailing DMK chief Karunanidhi. "His response to the medical interventions over the next 24 hours will determine the prognosis", Executive Director of the Hospital Dr Aravindan Selvaraj said in the terse two-paragraph release.
In 2006, when he assumed office as Chief Minister of Tamil Nadu, he became the oldest serving Chief Minister of Tamil Nadu.
Later, on July 31 the hospital indicated that Karunanidhi may have to have an extended stay at the hospital due to age-related overall decline in his general health, altered liver function and haematological parameters. India and particularly Tamil Nadu will miss him immensely. "I pray for his soul".
Former Jammu and Kashmir Chief Minister Omar Abdullah, former Uttar Pradesh Chief Minister Akhilesh Yadav and former Karnataka Chief Minister B S Yeddyurappa gave their condolences after Karunanidhi's passing.
Today India lost one of its greatest sons.
Born on June 3, 1924 at Thirukkuvalai into a family of Nadaswaram exponents who had traditionally played in temples, Karunanidhi, who was inclined towards Periyar E.V. Ramasamy's atheism and rationalism, joined his self-respect movement as a teenager.
August 10, 1942: As self-styled leader of "Tamil Nadu Tamil Maanavar Mandram", launches "Murasoli" in Tamil as handwritten manuscript.More news: Britain to adop new opt-out system for organ donation
More news: Trump Mueller investigation: President could take LEGAL ACTION against any court demands
More news: Brown says McLaren was 'pretty close' to signing Ricciardo
A founder member of the DMK when the party was formed in 1949.
July 1953: Arrested for the "Kallakudi Agitation", demanding renaming of Dalmiyapuram railway station as part of the anti-Hindi agitation, along with poet Kannadasan and others; Karunanidhi was convicted for six months for that stir.
February 1954: Returns to Chennai to a hero's welcome at Egmore station.
When the DMK entered the electoral fray in 1957 with demands for Dravidanadu-secession from India-the party was still unrecognised, but 33-year-old Karunanidhi won from Kulithalai constituency.
In 1961, he became the DMK treasurer and a year later he became the opposition's deputy leader in the state assembly. It is often said that he was just 14 when he became actively involved in politics inspired by the speeches of Alagirisamy of the Justice Party.
27 January 1989 - 30 January 1991: 3rd term as chief minister. Now, he has completed 60 years as a legislator after winning the 13 assembly elections without break.
This has not gone down well with the DMK cadres as well as the majority of people of TN.
April 28, 2009: Goes on a sudden, indefinite fast at Anna Square on the Marina in Chennai to press the Sri Lankan government to announce a ceasefire in its war against the Tamil militants in the Island's North.
Deeply saddened at the passing away of Kalaignar M Karunanidhi.