Earlier this year, Trebek revealed that he underwent a surgery to remove blood clots on his brain, but has since thankfully recovered.
First on Trebek's short list is 28-year-old Alex Faust, who is now working as the announcer for the L.A. Kings.
Faust, 28, took over play-by-play duties for the National Hockey League team on FOX Sports West in 2017.
Faust has experience replacing a legend - at 28 years old, he stepped into the Kings' play by play role in 2017, replacing Bob Miller, who retired after a 44-year broadcasting career.
Trebek also suggested Laura Coates, an attorney who serves as a legal voice for CNN, as another potential replacement. "She's African-American and she appears on some of the cable news shows from time to time".More news: Bernie Sanders Thanks the Koch Brothers For ‘Accidentally’ Supporting Healthcare For All
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Both expressed surprise and thanks on Twitter shortly after the host's comments aired.
After Levin asked him if he can imagine life without the show, Trebek said, "Sure".
Coates tweeted that she was "incredibly honored & humbled" at the mention, in part just to know Trebek "knows who I am".
Last February, Trebek also made headlines when he hilariously recited Kanye West and Drake lyrics on the show.
In an interview with TMZ's Harvey Levin, the iconic, Canadian-born game show host said that he could be done in 2020 when his current contract runs out.