Khamenei used a speech to foreign ministry officials to reject any renewed talks with the United States after President Donald Trump's decision to withdraw from a 2015 worldwide deal over Iran's nuclear programme. The same threat was earlier voiced by President Hassan Rouhani.
Iran's Supreme Leader Ayatollah Ali Khamenei has said that no country in the region will export oil if Iran's exports are stopped.
After the USA pulled out of the nuclear agreement, Iran made clear that it wants to keep the deal alive, but only if the remaining five powers can guarantee that Iran will not face economic isolation under the sanctions that the US has started to revive.
Even though Rouhani did not mention the Strait of Hormuz, his comments were nonetheless seen as a threat to the narrow strategic passageway located between Iran and Oman, where at least 18.5m barrels of oil were transported every day in 2016, according to a United States energy department report.
"Peace with Iran would be the mother of all peace and war with Iran would be the mother of all wars".
Current and former US officials said the campaign paints Iranian leaders in a harsh light, at times using information that is exaggerated or contradicts other official pronouncements, including comments by previous administrations.
Iranian President Hassan Rouhani had previously hinted that Tehran could shut the Strait of Hormuz - a strategic waterway that handles as much as 20 percent of the world's oil.More news: PM calls premiers to autumn meeting to reduce internal Canadian trade barriers
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"As I have previously said, we can not trust in the words of the United States and even in their signature, so negotiations with the United States are useless", Khamenei told a gathering of Iranian diplomats in Tehran.
Zarif expressed confidence that Iran would be able to overcome problems through unity and coherence and by relying on the Leader's guidelines and public support.
Rouhani's apparent threat earlier this month to disrupt oil shipments from neighboring countries came in reaction to efforts by Washington to force all countries to stop buying Iranian oil.
"Although the current American government does not seem to speak of a military threat, according to precise information it has been trying to persuade the US military to launch a military invasion (of Iran)", Baqeri said.
Mr. Netanyahu, a steadfast opponent of the nuclear deal since it was signed in 2015, in response accused Iran of "trying to conquer" the Middle East with its military presence in Syria.
But it has since eased its stance, saying it may grant sanction waivers to some allies that are particularly reliant on Iranian supplies.