The Englishman now has an average of 5.83 shots per 90 - more than any other player in the Premier League this season - but a slightly lower conversion rate of 15.15%.
City proved too hot to handle for Spurs on a freezing cold night in Manchester.
Kane has claimed the Golden Boot in each of the last two seasons, but following an ankle injury which kept him out for three weeks, he faces a struggle to overtake Salah with just six games to go.
Steve Wilson: "Let's get this straight, Manchester City have been fantastic this season - unbelievable".
"Tottenham is a fantastic team, they have great pressure". That margin has more or less remained the same since, and City have shown that they deserve to win the title. But they know I am still there, supporting until the end.
"We reduced the gap and we are competing. He's doing well, he's training and he only needs to wait for his opportunity". "We need to show ourselves that we can compete". I think Harry is a very honest person, he's not going to lie about this situation. It is not just me wanting to build some sort of image about us.
"I do think that we are always looking to respond in that way on the pitch", Kompany said.More news: Special counsel has evidence Michael Cohen traveled to Prague: McClatchy
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However, Tottenham would later launch a successful appeal against the decision and the Premier League have since announced Kane has been awarded the goal.
Manchester City will win a third Premier League title if they beat both Spurs and then Swansea City at home on April 22, but their skipper wants them to do it in the same style they have exhibited all season, starting at Wembley.
Since losing at the Etihad Stadium in December, Spurs are unbeaten in 14 league games (W11, D3).
City thrashed Spurs 4-1 when the sides met earlier in the season in the midst of a record 18-game winning run that amassed their commanding lead at the top of the table.
"It was also Christian who managed to pick up five yellow cards this season despite never attempting a single tackle, Christian who did the worst free-kick anyone had ever seen while playing for England against Iceland, and who scored that unbelievable own goal against Swansea back in 2015".
City have suffered their worst week since Guardiola took charge with three successive defeats for the first time under the Catalan coach.