City beat Tottenham Hotspur 3-1 on Saturday and have won 28 of their 33 matches.
United, fresh off a win in the Manchester derby, will be looking to keep the momentum going despite the fact they have little to play for at this stage of the season.
Manchester City need just 13 points from their last five games to reach the 100-point mark in the Premier League; something that has never been achieved in the English top-flight (based on three points for a win).
The Baggies are sitting at the base of the English Premier League table standings and will find it hard to stop a Manchester United side that is pushing to finish second in the league this year.
The Catalan, who now has won three titles in three different countries after three La Liga triumphs with Barcelona and three Bundesliga crowns with Bayern Munich, admitted his EPL title was one of his best achievements.
"They won the title because they were the best team". The defeat at Old Trafford helped the Etihad outfit mathematically win the Premier League.More news: Commonwealth Games community impact
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Guardiola, who sealed his seventh league title across three clubs in nine years of management, was playing golf with professional Tommy Fleetwood as the trophy was decided.
Because of goal difference, United realistically needed to win all of their six remaining games and hope City lost their last five matches. "I saw lots of people [players] in the moon because we won against Manchester City like to win against Manchester City was the most important thing of the season".
Mourinho admitted that City deserve to be champions but dismissed suggestions that United had handed the title to their rivals by losing on Sunday.
"We didn't want [to play] or couldn't play simple, everything was slow, one more flick, trick, turn".
West Brom had lost eight of their previous nine games and last won on January 13.
Mata knows how significant it could be if this year's team win the trophy in the coming weeks, even if Spurs represent hard opponents at Wembley. They are unbeaten in their last four versus Bournemouth (3-1-0) since a 2-1 loss at Dean Court in the first Premier League match between the teams in 2015.