"We can not take such risks", he said at a forum.
The Syrian government has also categorically denied the accusation.
US allies have offered strong words of support for Washington but no clear military plans have yet emerged.
The coordinated strikes were in response to the Syrian regime's chemical weapons attack on civilians in Douma, which allied governments say killed at least 60 people and left hundreds more injured over the weekend.
"Russia can complain all it wants about fake news, but no one is buying its lies and its coverups", she said.
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Here's who Russian Federation has blamed this week for the alleged chemical attack that killed dozens, including many children.
Konashenkov said the Syrian rescue group known as the White Helmets were instructed by London in the days before the attack to plan a "provocation", Tass reported. This is written in his statement, published on the facebook page of the embassy.
The US and its allies believe the Syrian regime was behind the attack, but Russian Federation has long insisted it was staged by rebels in an attempt to provoke further Western intervention. It cited the Russian Ministry of Defense.
In April previous year, the United States launched cruise missile attacks against a Syrian air base.
Russia's ambassador to the United Nations, Vassily Nebenzia, told reporters "The situation (in Syria) is very unsafe". "The immediate priority is to avert the danger of war", he told reporters.
A first team of experts from the global Organisation for the Prohibition of Chemical Weapons has arrived in Syria, U.N. Secretary-General Antonio Guterres said. Vladimir Shamanov, who chairs the defence committee of Russia's lower house, said the vessels had departed the base for their own safety, which was "normal practice" when there were threats of attack. -Russian showdown. Apart from Macron's phone conversation with Putin, NATO members Germany and the Netherlands have said they will not take part in any military action.