Liverpool remain third in the table but are now five points adrift of United.
The game, which is being broadcast on Sky Sports, will have a huge influence on who finishes second in the Premier League.
I would think Roberto Firmino will be the key man.
Marcus Rashford scored twice within 25 minutes before an Eric Bailly own goal gave Liverpool hope midway through the second half.
Mourinho often sets up to frustrate top opponents, and it was no different on Saturday-they sat deep, drew Liverpool out, and put long balls over the top to pick on Dejan Lovren and Trent Alexander-Arnold.More news: Catch a Louisiana high school senior on American Idol
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"The United player had time to get his arm out of the way and that was a clear spot kick for me, but Liverpool should not blame the referee for what was a terrible defeat".
While Rose could replace Luke Shaw at United, Milinkovic-Savic could fill the void created by the soon-to-retire Michael Carrick and Marouane Fellaini, who is yet to sign a new deal with the Red Devils and could leave on a free at the end of the campaign. It is just the all-round game is starting to become more clear.
"It's a pity that the manager is Mourinho because normally, he's an English player".
As such, many spectators would relish the opportunity to watch a rematch between the two Premier League titans at the pinnacle of European competition in Kiev this May, including former Arsenal man Martin Keown.
It is really hard to do against a team like Manchester United. "It is good that I can be around Marcus to have a laugh and reassure him that it's going to come good and that if he gets a chance he will perform and he has done that".
However, the Reds failed to take anything from the game with the side still yet to see victory at Old Trafford since 2014.