Oprah's best friend Gayle King was also moved by her speech and told the Times, "I thought that speech was incredible".
The well-received speech fueled more speculation Winfrey is considering a presidential campaign in 2020.
Chrissy Teigen was one of the many stars to respond directly, with a simple 'ew go away.' Alyssa Milano directed Ivanka to the Time's Up legal fund that will help her father's accusers with their expenses.
A spokesman for President Trump said Monday he would welcome a challenge from Oprah Winfrey - or anyone else, for that matter. Winfrey closed her impassioned speech with a message to young girls, "A new day is on the horizon". She said, "Do you think I'll be that successful?' I said 'Lady, you're going to cost me a lot of money but you are going to shoot the lights out, '" said Swanson.
She added: 'I've interviewed and portrayed people who've withstood some of the ugliest things life can throw at you, but the one quality all of them seem to share is an ability to maintain hope for a brighter morning, even during our darkest nights.
Winfrey delivered a powerful and inspiring speech addressing sexual harassment in which she denounced sexism and racism.More news: WNY native named to US Olympic men's ice hockey team
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Winfrey also praised the women who have spoken out against sexual abusers, a statement that by its nature includes the almost two dozen women who came forward against Trump.
Grant said America has already proven it's not averse to voting for a celebrity. I've been on her show ... Her reach is beyond the minority community.
Meryl Streep, 68, wants Winfrey to run, adding: "I don't think she had any intention but now she doesn't have a choice".
When she was asked by the L.A. Times if she was considering running for President in 2020, her answer was pretty cryptic.
MSNBC host Chris Hayes tweeted in response to Ivanka: "Who should tell her?"
"I'm sorry @IvankaTrump but unless you wish to call out your own father for his taped admission to assaulting women, your desire to join the sisterhood can not be taken with any validity..." "I also know that after years of watching the Oprah show, you always have the right to change your mind".