Ibuprofen can cause male infertility


The study took place across two countries, Denmark and France, and took a look at 31 adult men - all under the age of 35. "However, it's unknown whether the health effects of long-term ibuprofen use are reversible".

The condition, known as testosterone deficiency, is a failure of the testes to produce the male sex hormone testosterone, sperm or both.

While use of the painkiller for an occasional headache is unlikely to cause a problem, many people take the drug for long term management of pain. When researchers measured testosterone blood levels, they found them unchanged.

In March of previous year Jiri Dvorak, Fifa's former chief medical officer, warned of an "alarming trend" among elite football players to "abuse" legal painkillers such as ibuprofen.

The authors of the study have reportedly said that the drug disrupts male hormones and increases the likelihood that the affected male babies would be born with congenital malformations.

With regard to long-term ibuprofen use, "It is also of concern that men with compensated hypogonadism may eventually progress to overt primary hypogonadism".

Compensated hypogonadism has been linked to infertility and depression, as well as heart attacks and other cardiovascular problems. Researchers even tested ibuprofen on "bits of human testes" collected from organ donors and saw the same result: The drug hampered testosterone output.

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Within 14 days, the men taking daily ibuprofen exhibited an increase in luteinising hormones - which help regulate testosterone production - indicating the drug had impaired healthy testicular function, forcing the body to compensate by boosting testosterone levels.

"The safety and efficacy of active ingredients in these products has been well documented and supported by decades of scientific study and real-world use", he added. So, for the time being, I would urge men who need to take ibuprofen to continue to do so.

The popular over-the-counter painkiller ibuprofen widely used for aches and pains could make young men infertile by shrinking their testicles, scientists warn.

The author of the study points to the fact that a ideal result of the study has not been derived yet which can successfully explain the effects of long-term, constant as well as high-dosage exposure of ibuprofen on the body.

The adverse effects in the study weren't permanent.

Tots were up to 16 times more likely to have undescended testicles if their mum took more than one dose of aspirin, paracetamol or ibuprofen when expecting.