The Bengals will face the Minnesota Vikings in Minnesota this Sunday. His interception was one of the Vikings' few blemishes of the day, along with three penalties on the offensive line and two more holding calls on David Morgan and Jarius Wright.
Cincinnati gained just 161 yards for the day.
Lewis is 123-111 (.525) across 15 seasons as a head coach.
The Bengals entered the weekend with a record of 5-8 and went just 6-9-1 previous year. They drove 75 yards in nine plays on the opening drive, which was capped by Murray's 1-yard touchdown run.More news: When Harry met Barry: Prince interviews Obama for BBC radio
More news: President Trump Ban CDC from using these words "science-based" and "transgender"
More news: Terrorism suspect in custody following NYC explosion
The atmosphere is gloomy for the Cincinnati Bengals going into Week 15.
In a victory that was as important as it was euphoric, the Vikings beat the Cincinnati Bengals 34-7, drubbing a dilapidated and disinterested Bengals team to improve to 11-3.
Keenum completed 20 of 23 passes, including seven easy tosses to McKinnon for 114 yards in the first 100-yard receiving game for a Vikings running back since Onterrio Smith on September 26, 2004, against Chicago. They pulled starting quarterback Case Keenum for Teddy Bridgewater, who had not played since the 2015 season after a gruesome preseason injury a year ago. A fan favorite, he received a standing ovation from the home crowd. Bridgewater's first pass was intercepted, a high throw that bounced off McKinnon's hands and into the arms of strong safety Shawn Williams deep in Vikings territory.
The Vikings have averaged 132.2 rushing yards per game and allowed an average of 60.7 rushing yards per game this season. CB Dre Kirkpatrick, RB Joe Mixon and LB Vontaze Burfict all were inactive for Cincinnati due to concussions.